Elevated steroid sulfatase expression in breast cancers

Corticosteroid side effects may cause weight gain, water retention, flushing (hot flashes), mood swings or insomnia, and elevated blood sugar levels in people with diabetes. Any numbness or mild muscle weakness usually resolves within 8 hours in the affected arm or leg (similar to the facial numbness experienced after dental work). Patients who are being treated for chronic conditions (., heart disease, diabetes, rheumatoid arthritis) or those who cannot temporarily discontinue anti-clotting medications should consult their personal physician for a risk assessment.

Elevated alkaline phosphatase is most commonly caused by liver disease or bone disorders. Testing for ALP primarily consists of obtaining a blood sample from a patient along with several other tests for the disorder in question that may be associated with the increase in ALP in the blood serum. [11] It is possible to distinguish between the different forms (isoenzymes) of ALP produced by different types of tissues in the body, in order to pinpoint what's causing the increase of ALP, in order to treat the patient for either liver disease or bone disorder. A more rapid way for testing ALP concentration is by using p -nitrophenyl phosphate as substrate. [12] The required volume of serum is 5 cubic mm. for each testing. The sample is first incubated for 30 min. at 38 °C, in a buffered solution in the presence of p -nitrophenyl phosphate. By the action of ALP, phosphate groups are removed from the substrate and para - nitrophenol is liberated giving off a yellow color in solution which can be measured spectrophotometrically. [13]

Hemoglobin levels are amongst the most commonly performed blood tests, usually as part of a full blood count or complete blood count. The test is rather simple. The technician draws blood from a vein; from the inside of the elbow or the back of the hand, and the puncture site is cleaned with antiseptic. He or she inserts a small needle into the vein and collects the blood in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation, and once the tech collects the blood, they will remove the needle. 

Elevated steroid sulfatase expression in breast cancers

elevated steroid sulfatase expression in breast cancers

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