An acute myopathy has been observed with the use of high doses of corticosteroids, most often occurring in patients with disorders of neuromuscular transmission (eg, myasthenia gravis ), or in patients receiving concomitant therapy with neuromuscular blocking drugs (eg, pancuronium). This acute myopathy is generalized, may involve ocular and respiratory muscles, and may result in quadriparesis . Elevation of creatinine kinase may occur. Clinical improvement or recovery after stopping corticosteroids may require weeks to years.
Dosage for Kenalog 10 Injection is individualized based on the condition and patient response. Kenalog 10 Injection may interact with aminoglutethimide, birth control pills, hormone replacement therapy, blood thinners, cyclosporine, digoxin, insulin or diabetes medications you take by mouth, isoniazid, rifampin, seizure medication, antibiotics, aspirin, or other NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications you are taking. Kenalog 10 Injection should be used during pregnancy only if prescribed. This medication may be harmful to a fetus. Infants born to mothers who have received corticosteroids during pregnancy should be observed for signs of hypoadrenalism. This medication can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.
Sounds like they had a DeQuervain’s injection (if it’s intratendinous instead of just under the tendon sheath there can be a lot of resistance…especially if using a tuberculin syringe/needle), and then had either a trigger thumb injection or an intraarticular injection of the 1st carpometacarpal joint. Either way, they shouldn’t have had “nerve damage” from either injection. The “nerve damage” was probably already there. Without a pre- and post-injection EMG/NCS, it’s impossible to know for sure. The skin atrophy and other signs can be relatively common with kenalog and other insoluble steroids. I don’t what the “thumb locking” is unless the patient means trigger thumb. Some physicians will use sterile saline injections in the atrophied area to speed up the recovery.