Kortikosteroidi za alergiju

Monensin A manifestuje naklonost ka formiranju kompleksa sa monovalentnim katjonima kao što su Li + , Na + , K + , Rb + , Ag + and Tl + [9] [10] [11] [12] . Monensin A ima sposobnot transportovanja tih katjona kroz lipidne membrane ćelija, što mu daje značajnu ulogu Na + /H + antitransportera . On blokira intraćelijski proteinski transport, i poseduje antibiotička , antimalarijska , i druga biološka svojstva. [13] . Antibakteriske osobine Monensina i njegovih derivata su rezultat njihove sposobnosti da transportuju metalne katjone kroz ćeliske i intraćeliske membrane . [14] [15] [16] .

The severity of these complications correlates with the dosage, duration of use, and the potency of the steroid prescribed. While the incidence of steroid-induced myopathy does not appear to be directly related to the dosage of steroid prescribed nor the duration of use, it appears to be more prevalent with the use of steroids containing a 9-alpha fluorine configuration, such as triamcinolone (Aristocort®). The relationship between hypertensive side effects and the duration of therapy is also not very clear; steroids should be prescribed with greater caution in the elderly, in those individuals with known hypertension, and when compounds with greater mineralocorticoid properties are prescribed. As hyperglycemia is a well-known complication of corticosteroid use, oral steroids should be prescribed with caution in the diabetic population.

Kortikosteroidi za alergiju

kortikosteroidi za alergiju

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